Nbiocell

Glidacell

Glidacell is a nanodisc particle formed by the self-assembly of long-chain
phospholipids and short-chain surfactants. The bilayer core mimics biomembranes,
while the micellar rim stabilizes the particle structure.
This architecture enables diverse applications from membrane protein studies
to transdermal delivery systems.

Structural Features

Disc-like Shape

Flat, pancake-like morphology
Bilayer Core

Two phospholipid layers forming a stable inner membrane
Stable Rim

Micellar edges provide strong structural stability

Key Properties

Thermal & Structural Stability
- High thermodynamic stability due to bilayer formation
- Ideal protection for sensitive active ingredients
- Suitable for delivering poorly soluble compounds
Excellent Diffusion Capability
- Nano-sized structure smaller than conventional liposomes
- Rapid dispersion and absorption
- Efficient penetration into skin and biological tissues
Continuous Process Compatibility
- Continuous production enabled by microfluidic systems
- Closed-process manufacturing maintains high purity
- Optimized for industrial-scale mass production

Nanoparticle Characterization

Glidacell (TEM)
Glidacell (DLS)
Comparison with Others

Skin Penetration Study

Glidacell
General Lipid Nanoparticles

Related Publications

No	Title
1	Precision transition of bicelle to liposome as carriers of a hydrophilic biologically active compound by microfluidic mixing integrated micro-structure (Int. J. Precis. Eng. Manuf. - Green Technol., 2024, 11(2): 537–548)
2	Preparation of planar lipid bilayer membrane by utilizing bicelles and its characterization (Kagaku Kogaku Ronbunshu, 2022, 48(5): 175–181)
3	Controlled-rate slow freezing with lyoprotective agent to retain the integrity of lipid nanovesicles during lyophilization (Sci. Rep., 2021, 11: 24354)
4	Continuous preparation of bicelles using hydrodynamic focusing for bicelle-to-vesicle transition (Micro Nano Syst. Lett., 2021, 9(1): 7)
5	Continuous synthesis of bicelles in microfluidic systems (Langmuir, 2021, 37(42): 12255–12262)
6	Vesicle preparation by simple dilution of bicelle solution (Biochem. Eng. J., 2020, 162: 107725)
7	Systematic characterization of DMPC/DHPC self-assemblies in aqueous solution (Colloids and Interfaces, 2018, 2(4): 73)