Liposome

Advanced nano drug-delivery platform — Liposome

  • R&D
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  • Liposome

Liposome

Liposomes are spherical micro/nanoparticles composed of phospholipid bilayers,
structurally similar to human cell membranes.
Their biomimetic and biodegradable characteristics ensure excellent biocompatibility,
while safely encapsulating a wide variety of therapeutic compounds.
As a result, liposomes are regarded as an essential drug delivery system (DDS)
in advanced industrial fields such as pharmaceuticals, cosmetics, and functional foods.

Liposome structure

Structural Features

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    Spherical Nanoparticles
    Spherical structure that mimics cellular membranes
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    Encapsulation of Both Hydrophilic & Lipophilic Agents
    Hydrophilic compounds in the core, lipophilic compounds in the bilayer membrane
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    Excellent Structural Stability
    High stability ensured by bilayer integrity

Key Properties

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    Thermal & Structural Stability
    • Maintains particle integrity even under elevated temperatures
    • Robust structural properties maximize delivery stability
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    Precision Particle Control
    • Proprietary technology ensures highly uniform particle size distribution
    • Tunable design for various applications and delivery targets
    • Improved delivery efficiency and enhanced bioavailability
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    Continuous Manufacturing Compatibility
    • Compatible with microfluidic-based continuous production
    • Closed system maintains purity throughout the process
    • Suitable for cost-efficient industrial mass production

Nanoparticle Characterization

  • Temperature-dependent stability graph
    Temperature Stability Graph (B9)
  • Liposome DLS
    Liposome (DLS)
  • Liposome TEM
    Liposome (TEM)
  • Liposome TEM
    Liposome (TEM)

Related Publications

No Title
1 Bromelain-decorated nanoscale liposomes for mucus permeation and intestinal absorption in oral drug delivery (ACS Appl. Nano Mater., 2023, 7(1): 348–357)
2 Precise control of liposome size based on solvent type and membrane properties (Sci. Rep., 2023, 13(1): 4728)
3 Controlled-rate slow freezing with lyoprotective agents to retain the integrity of lipid nanovesicles during lyophilization (Sci. Rep., 2021, 11: 24354)
4 Physicochemical characterization of phospholipid vesicles prepared in CO₂/water systems at high pressure (Biointerphases, 2015, 10(3))
5 Method for preparing liposome frozen powder capable of efficiently retaining its bilayer structure (US Patent: US10660853B2)